Special Lecture

Interplay of Stress Signaling and Mitochondria in Hepatotoxicity

Prof. Neil Kaplowitz

Professor Kaplowitz is founder and ongoing Center Director of the NIDDK Liver Center Core facilities. He has been investigating hepatotoxicity for more than three decades, especially in the areas of GSH metabolism, oxidative, mitochondrial toxicity, acetaminophen, and has made important discoveries which have lead him to transition over the past decade into related areas of signal transduction and transcriptional regulation in the area of toxin and alcohol- induced liver injury. As a physician scientist he has had the unique opportunity to bridge basic science and clinical liver disease and he remains well versed in the whole spectrum of this field. Currently his research activities are mainly divided between the alcohol homocysteine, ER stress and the Signal Transduction in Hepatotoxicity.