Publications

2024

The role of forkhead box M1-methionine adenosyltransferase 2A/2B axis in liver inflammation and fibrosis.
Yang, Bing; Lu, Liqing; Xiong, Ting; Fan, Wei; Wang, Jiaohong; Barbier-Torres, Lucia; Chhimwal, Jyoti; Sinha, Sonal; Tsuchiya, Takashi; Mavila, Nirmala; Tomasi, Maria Lauda; Cao, DuoYao; Zhang, ...
Nature communications
2024

The power lies in the glycans
Unione, L; Jiménez-Barbero, J;
ELIFE
2024

Consensus document on the implications of standardization of BCG supply in the management of patients with non-muscle-invasive bladder cancer.
Rodriguez Faba, O; Fernandez Gomez, J M; Guerrero-Ramos, F; Alvarez-Maestro, M; Ledo Cepero, M J; Unda Urzaiz, M; Martinez-Pineiro, L; Cozar Olmo, J M; Redorta, J Palou; Alvarez-Ossorio, J L;
Actas urologicas espanolas
2024

Hypoxic Memory Mediates Prolonged Tumor-Intrinsic Type I Interferon Suppression to Promote Breast Cancer Progression
Iriondo, O; Mecenas, D; Li, YL; Chin, CR; Thomas, A; Moriarty, A; Marker, R; Wang, YJ; Hendrick, H; Amzaleg, Y; Ortiz, V; Mackay, M; Dickerson, A; Lee, G; Harotoonian, S; Benayoun, BA; Smith, ...
CANCER RESEARCH
2024

TIMP1 mediates astrocyte-dependent local immunosuppression in brain metastasis acting on infiltrating CD8+ T cells.
Priego, Neibla; de Pablos-Aragoneses, Ana; Perea-Garcia, Maria; Pieri, Valentina; Hernandez-Oliver, Carolina; Alvaro-Espinosa, Laura; Rojas, Andrea; Sanchez, Oliva; Steindl, Ariane; Caleiras, ...
Cancer discovery
2024

Systemic messenger RNA replacement therapy is effective in a novel clinically relevant model of acute intermittent porphyria developed in non-human primates
Cordoba, KM; Jericó, D; Jiang, L; Collantes, M; Alegre, M; García-Ruiz, L; Manzanilla, O; Sampedro, A; Herranz, JM; Insausti, I; de la Cuesta, AM; Urigo, F; Alcaide, P; Morán, M; Martin, MA; ...
GUT
2024

Ice recrystallization inhibitors enable efficient cryopreservation of induced pluripotent stem cells: A functional and transcriptomic analysis
Mommaerts, K; Okawa, S; Schmitt, M; Kofanova, O; Turner, TR; Ben, RN; Del Sol, A; Mathieson, W; Schwamborn, JC; Acker, JP; Betsou, F;
STEM CELL RESEARCH
2024

Isolation of small extracellular vesicles from regenerating muscle tissue using tangential flow filtration and size exclusion chromatography
Gurriaran-Rodriguez, U; De Repentigny, Y; Kothary, R; Rudnicki, MA;
SKELETAL MUSCLE
2024

Detecting expressed genes in cell populations at the single-cell level with scGeneXpress
Jung, SS; Barlier, C; Perez, AM; del Sol, A;
BRIEFINGS IN BIOINFORMATICS
2024

The Neoangiogenic Transcriptomic Signature Impacts Hepatocellular Carcinoma Prognosis and Can Be Triggered by Transarterial Chemoembolization Treatment
Critelli, RM; Casari, F; Borghi, A; Serino, G; Caporali, C; Magistri, P; Pecchi, A; Shahini, E; Milosa, F; Di Marco, L; Pivetti, A; Lasagni, S; Schepis, F; De Maria, N; Dituri, F; Martínez-Chantar, ...
CANCERS
2024

A resurrected ancestor of Cas12a expands target access and substrate recognition for nucleic acid editing and detection
Jabalera, Y; Tascon, I; Samperio, S; Lopez-Alonso, JP; Gonzalez-Lopez, M; Aransay, AM; Abascal-Palacios, G; Beisel, CL; Ubarretxena-Belandia, I; Perez-Jimenez, R;
NATURE BIOTECHNOLOGY
2024

The Therapeutic Potential of Adipose-Derived Mesenchymal Stem Cell Secretome in Osteoarthritis: A Comprehensive Study
González-Cubero, E; González-Fernández, ML; Esteban-Blanco, M; Perez-Castrillo, S; Pérez-Fernández, E; Navasa, N; Aransay, AM; Anguita, J; Villar-Suárez, V;
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2024

Albumin reprograms the B cell transcriptional landscape and improves neutrophil antimicrobial function in patients with decompensated cirrhosis
Clària, J; Aguilar, F; Lozano, JJ; Jiménez-Gracia, L; Nieto, JC; Romero-Grimaldo, B; Marcos-Fa, X; Giarracco, E; Weiss, E; Trebicka, J; Hernández, I; Fernandez, J; Casulleras, M; López-Vicario, ...
JHEP REPORTS
2024

Functional Variation in Human CAZyme Genes in Relation to the Efficacy of a Carbohydrate-Restricted Diet in IBS Patients.
Zamfir-Taranu, Andreea; Loscher, Britt-Sabina; Carbone, Florencia; Hoter, Abdullah; Esteban Blanco, Cristina; Bozzarelli, Isotta; Torices, Leire; Routhiaux, Karen; Van den Houte, Karen; Bonfiglio, ...
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
2024

Sensitizing cholangiocarcinoma to chemotherapy by inhibition of the drug-export pump MRP3.
Asensio, Maitane; Briz, Oscar; Herraez, Elisa; Perez-Silva, Laura; Espinosa-Escudero, Ricardo; Bueno-Sacristan, Diego; Peleteiro-Vigil, Ana; Hammer, Helen; Potz, Oliver; Kadioglu, Onat; Banales, ...
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
2024

Biotin-based strategies to explore the world of ubiquitin and ubiquitin-like modifiers
Merino-Cacho, L; Barroso-Gomila, O; Hernandez-Sánchez, S; Ramirez, J; Mayor, U; Sutherland, JD; Barrio, R;
CHEMBIOCHEM
2024

Sucrase Isomaltase Dysfunction Reduces Sucrose Intake in Mice and Humans.
Aldiss, Peter; Torices, Leire; Ramne, Stina; Jorgensen, Marit Eika; Sucrase-Isomaltase Working Group; DAmato, Mauro; Andersen, Mette K; Bonfiglio, Ferdinando; Burm, Hayley; Esteban Blanco, Cristina; ...
Gastroenterology
2024

Characterization of Extracellular Vesicles from Human Saliva: Effects of Age and Isolation Techniques
Reseco, L; Molina-Crespo, A; Atienza, M; Gonzalez, E; Falcon-Perez, JM; Cantero, JL; Neri, C;
CELLS
2024

Müller glial cells located in the peripheral retina are more susceptible to high pressure: implications for glaucoma
Pereiro, X; Ruzafa, N; Azkargorta, M; Elortza, F; Acera, A; Ambrósio, AF; Santiago, AR; Vecino, E;
CELL AND BIOSCIENCE
2024

Anti-miR-873-5p improves alcohol-related liver disease by enhancing hepatic deacetylation via SIRT1
Rodríguez-Agudo, R; González-Recio, I; Serrano-Maciá, M; Bravo, M; Petrov, P; Blaya, D; Herranz, JM; Mercado-Gómez, M; Rejano-Gordillo, CM; Lachiondo-Ortega, S; Gil-Pitarch, C; Azkargorta, M; ...
JHEP REPORTS
2024

SUMOylation modulates eIF5A activities in both yeast and pancreatic ductal adenocarcinoma cells
Seoane, R; Lama-Diaz, T; Romero, AM; El Motiam, A; Martinez-Ferriz, A; Vidal, S; Bouzaher, YH; Blanquer, M; Tolosa, RM; Mewa, JC; Rodriguez, MS; Garcia-Sastre, A; Xirodimas, D; Sutherland, JD; ...
CELLULAR & MOLECULAR BIOLOGY LETTERS
2024

Improving Protein Expression, Stability, and Function with ProteinMPNN
Sumida, KH; Núñez-Franco, R; Kalvet, I; Pellock, SJ; Wicky, BIM; Milles, LF; Dauparas, J; Wang, J; Kipnis, Y; Jameson, N; Kang, AL; De La Cruz, J; Sankaran, B; Bera, AK; Jiménez-Osés, G; Baker, D;
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2024

Next-Generation Proteomics of Brain Extracellular Vesicles in Schizophrenia Provide New Clues on the Altered Molecular Connectome
Lorca, C; Fernandez-Rhodes, M; Milan, JAS; Mulet, M; Elortza, F; Ramos-Miguel, A; Callado, LF; Meana, JJ; Mur, M; Batalla, I; Vilella, E; Serra, A; Gallart-Palau, X;
BIOMEDICINES
2024

Glycosylium Ions in Superacid Mimic the Transition State of Enzyme Reactions
Armand, M; Nin-Hill, A; Ardá, A; Berrino, E; Désiré, J; Martin-Mingot, A; Michelet, B; Jiménez-Barbero, J; Blériot, Y; Rovira, C; Thibaudeau, S;
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2024

Recommendations for reproducibility of cerebrospinal fluid extracellular vesicle studies
Sandau, US; Magana, SM; Costa, J; Nolan, JP; Ikezu, T; Vella, LJ; Jackson, HK; Moreira, LR; Palacio, PL; Hill, AF; Quinn, JF; Van Keuren-Jensen, KR; Mcfarland, TJ; Palade, J; Sribnick, EA; Su, ...
Journal of Extracellular Vesicles
2024

Engineering hyaluronic acid-based nanoassemblies for monoclonal antibody delivery - design, characterization, and biological insights
López-Estévez, AM; Zhang, Y; Medel, M; Arriaga, I; Sanjurjo, L; Huck-Iriart, C; Abrescia, NGA; Vicent, MJ; Ouyang, DF; Torres, D; Alonso, MJ;
NANO RESEARCH
2024

Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site
Thompson, AJ; Wu, NC; Canales, A; Kikuchi, C; Zhu, XY; de Toro, BF; Cañada, FJ; Worth, C; Wang, SY; Mcbride, R; Peng, WJ; Nycholat, CM; Jiménez-Barbero, J; Wilson, IA; Paulson, JC;
CELL HOST & MICROBE
2024

Magnetic nanoradiotracers for targeted neutrophil detection in pulmonary arterial hypertension
Fadón-Padilla, L; de Alejo, CMP; Miguel-Coello, AB; Beraza, M; Di Silvio, D; Urkola-Arsuaga, A; Sánchez-Guisado, MJ; Aiestaran-Zelaia, I; Fernández-Méndez, L; Martinez-Parra, L; Ismalaj, E; ...
JOURNAL OF NANOBIOTECHNOLOGY
2024

The impact of glycosylation on the structure, function, and interactions of CD14.
Quintana, Jon Imanol; Delgado, Sandra; Rabano, Miriam; Azkargorta, Mikel; Florencio-Zabaleta, Mirane; Unione, Luca; Vivanco, Maria dM; Elortza, Felix; Jimenez-Barbero, Jesus; Arda, Ana;
Glycobiology
2024

Ancient and versatile CRISPR-Cas nuclease created with ancestral sequence reconstruction
Jabalera, Y; Perez-Jimenez, R;
NATURE BIOTECHNOLOGY
2024

SinCMat: A single-cell-based method for predicting functional maturation transcription factors
Barvaux, S; Okawa, S; del Sol, A;
STEM CELL REPORTS
2024

Extracellular vesicles in tumor-adipose tissue crosstalk: key drivers and therapeutic targets in cancer cachexia
Ramos, CC; Pires, J; Gonzalez, E; Garcia-Vallicrosa, C; Reis, CA; Falcon-Perez, JM; Freitas, D;
EXTRACELLULAR VESICLES AND CIRCULATING NUCLEIC ACIDS
2024

Allosteric control of dynamin-related protein 1 through a disordered C-terminal Short Linear Motif
Pérez-Jover, I; Rochon, K; Hu, D; Mahajan, M; Mohan, PM; Santos-Pérez, I; Gisasola, JO; Galvez, JMM; Agirre, J; Qi, X; Mears, JA; Shnyrova, AV; Ramachandran, R;
NATURE COMMUNICATIONS
2024

Interplay Between Substrate Polarity and Protein Dynamics in Evolved Kemp Eliminases
Peccati, F; Noey, EL; Houk, KN; Osuna, S; Jiménez-Osés, G;
CHEMCATCHEM
2024

Hepatic prohibitin 1 and methionine adenosyltransferase a1 defend against primary and secondary liver cancer metastasis
Fan, W; Cao, DY; Yang, B; Wang, JH; Li, XM; Kitka, D; Li, TWH; You, SY; Shiao, S; Gangi, A; Posadas, E; Di Vizio, D; Tomasi, ML; Seki, E; Mato, JM; Yang, HP; Lu, SC;
JOURNAL OF HEPATOLOGY
2024

Faecal biomarkers for diagnosis and prediction of disease course in treatment-naïve patients with IBD
Lundström, ML; Peterson, C; Hedin, CRH; Bergemalm, D; Lampinen, M; Magnusson, MK; Keita, AV; Kruse, R; Lindqvist, CM; Repsilber, D; DAmato, M; Hjortswang, H; Strid, H; Soederholm, JD; Öhman, ...
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
2024

Breast cancer: Prognostic value of "TN" status versus tumor gene expression profile
Arana, JAM; Estévez, IZ; Ruiz, JAL; Ruiz, MDV; Maseda, AL;
REVISTA DE SENOLOGIA Y PATOLOGIA MAMARIA
2024

"Analysis of veterinary drugs and pesticides in food using liquid chromatography-mass spectrometry"
Brandi, J; Siragusa, G; Robotti, E; Marengo, E; Cecconi, D;
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
2024

Interplay of chloride levels and palladium(ii)-catalyzed O-deallenylation bioorthogonal uncaging reactions
Dal Forno, GM; Latocheski, E; Navo, CD; Albuquerque, BL; St John, AL; Avenier, F; Jiménez-Osés, G; Domingos, JB;
CHEMICAL SCIENCE
2024

Serum identification of at-risk MASH: The metabolomics-advanced steatohepatitis fibrosis score (MASEF)
Noureddin, M; Truong, E; Mayo, R; Martínez-Arranz, I; Banales, JM; Mincholé, I; Arrese, M; Cusi, K; Arias-Loste, MT; Bruha, R; Romero-Gómez, M; Iruzubieta, P; Aller, R; Ampuero, J; Calleja, ...
HEPATOLOGY
2024

An in vitro analysis of the interaction between infliximab and granulocyte-monocyte apheresis
Rodríguez-Lago, I; Abecia, L; Seoane, I; Anguita, J; Cabriada, JL;
GASTROENTEROLOGIA Y HEPATOLOGIA
2024

Exploring galectin interactions with human milk oligosaccharides and blood group antigens identifies BGA6 as a functional galectin-4 ligand
Cagnoni, AJ; Massaro, M; Cutine, AM; Gimeno, A; Pérez-Sáez, JM; Cocco, MNM; Maller, SM; Di Lella, S; Jiménez-Barbero, J; Ardá, A; Rabinovich, GA; Mariño, K;
JOURNAL OF BIOLOGICAL CHEMISTRY
2024

Letter to the Editor: Serum identification of at-risk MASH: The metabolomics-advanced steatohepatitis fibrosis score (MASEF)
Noureddin, M; Truong, E; Mayo, R; Martínez-Arranz, I; Mincholé, I; Banales, JM; Arrese, M; Cusi, K; Arias-Loste, MT; Bruha, R; Romero-Gómez, M; Iruzubieta, P; Aller, R; Ampuero, J; Calleja, ...
HEPATOLOGY
2024

Novel Emerging Mechanisms in Acetaminophen (APAP) Hepatotoxicity
Hionides-Gutierrez, A; Goikoetxea-Usandizaga, N; Sanz-Garcia, C; Martinez-Chantar, ML; Cubero, FJ;
LIVER INTERNATIONAL
2024

Exploring glycan-lectin interactions in natural-like environments: A view using NMR experimentsinside cell and on cell surface.
Bertuzzi, Sara; Lete, Marta G; Franconetti, Antonio; Diercks, Tammo; Delgado, Sandra; Oyenarte, Iker; Moure, Maria J; Nunez-Sancho, Reyes; Valverde, Pablo; Lenza, Maria Pia; Sobczak, Klaudia; ...
Chemistry (Weinheim an der Bergstrasse, Germany)
2024

Mechanistic Insights into Chloride-Dependent Uncaging Reaction of Propargyl and Allene-Protected Substrates by Pd-Complexes.
Ferreira, Thuany M; Navo, Claudio D; Agnes, Jonathan P; Cardozo, Filipe; de Oliveira, Daniela C; Zanotto-Filho, Alfeu; Jimenez-Oses, Gonzalo; Domingos, Josiel B;
Chemistry (Weinheim an der Bergstrasse, Germany)
2024

Preclinical protein signatures of Crohn's disease and ulcerative colitis: A nested case-control study within large population-based cohorts.
Granno, Olle; Bergemalm, Daniel; Salomon, Benita; Lindqvist, Carl Marten; Hedin, Charlotte R H; Carlson, Marie; Dannenberg, Katharina; Andersson, Erik; Keita, Asa V; Magnusson, Maria K; Eriksson, ...
Gastroenterology
2024

Opposed Aromatic Surfaces Behave as Independent Binding Sites for Carbohydrate Stacking: Analysis of Sandwich-like CH/π/CH Complexes
Díaz-Casado, L; Mann, E; Jiménez-Moreno, E; Villacampa, A; Montalvillo-Jiménez, L; Sánchez-García, C; Corzana, F; Jiménez-Barbero, J; Gómez, AM; Santana, AG; Asensio, JL;
JACS AU
2024

Different roles of the heterodimer architecture of galectin-4 in selective recognition of oligosaccharides and lipopolysaccharides having ABH antigens
Quintana, JI; Massaro, M; Cagnoni, AJ; Nuñez-Franco, R; Delgado, S; Jiménez-Osés, G; Mariño, KV; Rabinovich, GA; Jiménez-Barbero, J; Ardá, A;
JOURNAL OF BIOLOGICAL CHEMISTRY
2024

Fission of double-membrane tubes under tension
Spencer, RKW; Santos-Pérez, I; Shnyrova, A; Müller, M;
BIOPHYSICAL JOURNAL
2024

NMR investigations of glycan conformation, dynamics, and interactions
Angulo, J; Ardá, A; Bertuzzi, S; Canales, A; Ereño-Orbea, J; Gimeno, A; Gomez-Redondo, M; Muñoz-García, JC; Oquist, P; Monaco, S; Poveda, A; Unione, L; Jiménez-Barbero, J;
PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
2024

Unveiling the GT114 family: Structural characterization of A075L, a glycosyltransferase from Paramecium bursaria chlorella virus-1 (PBCV-1)
Laugieri, ME; Speciale, I; Gimeno, A; Lin, SC; Byers, BW; Poveda, A; Nunez-Franco, R; Iturrioz, I; Moure, MJ; Jimenez-Oses, G; Russo-Krauss, I; Notaro, A; Van Etten, JL; Lowary, TL; Jimenez-Barbero, ...
PROTEIN SCIENCE
2024

Akkermansia muciniphila-induced trained immune phenotype increases bacterial intracellular survival and attenuates inflammation
Peña-Cearra, A; Palacios, A; Pellon, A; Castelo, J; Pasco, ST; Seoane, I; Barriales, D; Martin, JE; Pascual-Itoiz, MA; Gonzalez-Lopez, M; Martín-Ruiz, I; Macías-Cámara, N; Gutiez, N; Araujo-Aris, ...
Communications Biology
2024

Biallelic variants in SNUPN cause a limb girdle muscular dystrophy with myofibrillar-like features
Iruzubieta, P; Damborenea, A; Ioghen, M; Bajew, S; Fernandez-Torrón, R; Töpf, A; Herrero-Reiriz, A; Epure, D; Vill, K; Hernández-Laín, A; Manterola, M; Azkargorta, M; Pikatza-Menoio, O; Pérez-Fernandez, ...
BRAIN
2024

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
Welsh, JA; Goberdhan, DCI; ODriscoll, L; Buzas, EI; Blenkiron, C; Bussolati, B; Cai, HJ; Di Vizio, D; Driedonks, TAP; Erdbrügger, U; Falcon-Perez, JM; Fu, QL; Hill, AF; Lenassi, M; Lim, SK; ...
JOURNAL OF EXTRACELLULAR VESICLES
2024

Roadmap to DILI research in Europe. A proposal from COST action ProEuroDILINet
Lucena, MI; Villanueva-Paz, M; Alvarez-Alvarez, I; Aithal, GP; Björnsson, ES; Cakan-Akdogan, G; Cubero, FJ; Esteves, F; Falcon-Perez, JM; Fromenty, B; Garcia-Ruiz, C; Grove, JI; Konu, O; Kranendonk, ...
PHARMACOLOGICAL RESEARCH
2024

p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway
Fondevila, MF; Novoa, E; Gonzalez-Rellan, MJ; Fernandez, U; Heras, V; Porteiro, B; Parracho, T; Dorta, V; Riobello, C; Lima, ND; Seoane, S; Garcia-Vence, M; Chantada-Vazquez, MP; Bravo, SB; ...
CELL REPORTS MEDICINE
2024

miRNA-221 and miRNA-483-3p Dysregulation in Esophageal Adenocarcinoma
Bozzarelli, I; Orsini, A; Isidori, F; Mastracci, L; Malvi, D; Lugaresi, M; Fittipaldi, S; Gozzellino, L; Astolfi, A; Räsänen, J; DErrico, A; Rosati, R; Fiocca, R; Seri, M; Krishnadath, KK; Bonora, ...
CANCERS
2024

Food phenolics and Lactiplantibacillus plantarum
Muñoz, R; de las Rivas, B; Rodríguez, H; Esteban-Torres, M; Reverón, I; Santamaría, L; Landete, JM; Sánchez-Arroyo, A; Plaza-Vinuesa, L; Jiménez, N; Curiel, JA;
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
2024

Unraveling Molecular Recognition of Glycan Ligands by Siglec-9 via NMR Spectroscopy and Molecular Dynamics Modeling
Atxabal, U; Nycholat, C; Pröpster, JM; Fernández, A; Oyenarte, I; Lenza, MP; Franconetti, A; Soares, CO; Coelho, H; Marcelo, F; Schubert, M; Paulson, JC; Jiménez-Barbero, J; Ereño-Orbea, J;
ACS CHEMICAL BIOLOGY
2024

Quantitative Analysis of the Human Semen Phosphorometabolome by 31P-NMR
Serrano, R; Martin-Hidalgo, D; Bilbao, J; Bernardo-Seisdedos, G; Millet, O; Garcia-Marin, LJ; Bragado, MJ;
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2024

Dissecting the Conformational Stability of a Glycan Hairpin
Yadav, N; Djalali, S; Poveda, A; Ricardo, MG; Seeberger, PH; Jiménez-Barbero, J; Delbianco, M;
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2024

Illuminating a Solvent-Dependent Hierarchy for Aromatic CH/π Complexes with Dynamic Covalent Glyco-Balances
Díaz-Casado, L; Villacampa, A; Corzana, F; Jiménez-Barbero, J; Gómez, AM; Santana, AG; Asensio, JL;
JACS AU
2024

S-Adenosylmethionine Negatively Regulates the Mitochondrial Respiratory Chain Repressor MCJ in the Liver
Barbier-Torres, L; Chhimwal, J; Kim, SY; Ramani, K; Robinson, A; Yang, HP; Van Eyk, J; Liangpunsakul, S; Seki, E; Mato, JM; Lu, SC;
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
2024

Comparative proteomic analysis of the changes in mare milk associated with different lactation stages and management systems
Blanco-Doval, A; Azkargorta, M; Iloro, I; Beaskoetxea, J; Elortza, F; Barron, JR; Aldai, N;
FOOD CHEMISTRY
2024

Enhancing the correlation between in vitro and in vivo experiments in dental implant osseointegration: investigating the role of Ca ions
Gavilán, FR; Cerqueira, A; Anitua, E; Muñoz, F; Arnáez, IG; Azkargorta, M; Elortza, F; Gurruchaga, M; Goñi, I; Suay, J; Tejero, R;
JOURNAL OF MATERIALS CHEMISTRY B
2024

Impaired Hepatic Very Low-Density Lipoprotein Secretion Promotes Tumorigenesis and Is Accelerated with Fabp1 Deletion
Newberry, EP; Molitor, EA; Liu, AL; Chong, KMY; Liu, XL; Alonso, C; Mato, JM; Davidson, NO;
AMERICAN JOURNAL OF PATHOLOGY
2024

High-throughput virtual search of small molecules for controlling the mechanical stability of human CD4
Reifs, A; Fernandez-Calvo, A; Alonso-Lerma, B; Schönfelder, J; Franco, D; Ortega-Muñoz, M; Casares, S; Jimenez-Lopez, C; Saa, L; Cortajarena, AL; De Sancho, D; San Sebastian, E; Perez-Jimenez, R;
JOURNAL OF BIOLOGICAL CHEMISTRY
2024

Strategy for the Enzymatic Acylation of the Apple Flavonoid Phloretin Based on Prior α-Glucosylation
Gonzalez-Alfonso, JL; Alonso, C; Poveda, A; Ubiparip, Z; Ballesteros, AO; Desmet, T; Jiménez-Barbero, J; Coderch, L; Plou, FJ;
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
2024

A Protein Misfolding Shaking Amplification-based method for the spontaneous generation of hundreds of bona fide prions
Erana, H; Sampedro-Torres-Quevedo, C; Charco, JM; Diaz-Dominguez, CM; Peccati, F; San-Juan-Ansoleaga, M; Vidal, E; Goncalves-Anjo, N; Perez-Castro, MA; Gonzalez-Miranda, E; Pineiro, P; Fernandez-Veiga, ...
NATURE COMMUNICATIONS
2024

Inhibition of BRD4 Attenuates ER Stress-induced Renal Ischemic-Reperfusion Injury
Diaz-Bulnes, P; Rodríguez, RM; Banon-Maneus, E; Saiz, ML; Bernet, CR; Corte-Iglesias, V; Ramirez-Bajo, MJ; Lazo-Rodriguez, M; Tamargo-Gómez, I; Rodrigues-Diez, RR; Sanz, AB; Diaz-Corte, C; Ruiz-Ortega, ...
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
2024

Cross-Validation of Metabolic Phenotypes in SARS-CoV-2 Infected Subpopulations Using Targeted Liquid Chromatography-Mass Spectrometry (LC-MS)
Whiley, L; Lawler, NG; Zeng, AX; Lee, A; Chin, ST; Bizkarguenaga, M; Bruzzone, C; Embade, N; Wist, J; Holmes, E; Millet, O; Nicholson, JK; Gray, N;
JOURNAL OF PROTEOME RESEARCH
2024

SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
Lachiondo-Ortega, S; Rejano-Gordillo, CM; Simon, J; Lopitz-Otsoa, F; Delgado, TC; Mazan-Mamczarz, K; Goikoetxea-Usandizaga, N; Zapata-Pavas, LE; García-del Río, A; Guerra, P; Peña-Sanfélix, ...
CELL REPORTS
2024

Stratification of Sepsis Patients on Admission into the Intensive Care Unit According to Differential Plasma Metabolic Phenotypes
Lodge, S; Litton, E; Gray, N; Ryan, M; Millet, O; Fear, M; Raby, E; Currie, A; Wood, F; Holmes, E; Wist, J; Nicholson, JK;
JOURNAL OF PROTEOME RESEARCH
2024

Novel TLR4-Activating Vaccine Adjuvant Enhances the Production of Enterococcus faecium-binding Antibodies
Franco, AR; Sadones, O; Romerio, A; Artusa, V; Shaik, MM; Pasco, ST; Italia, A; DAmato, S; Anguita, J; Huebner, J; Romero-Saavedra, F; Peri, F;
JOURNAL OF MEDICINAL CHEMISTRY
2024

Characterization of preovulatory follicular fluid secretome and its effects on equine oocytes during in vitro maturation
Luis-Calero, M; Marinaro, F; Fernández-Hernández, P; Ortiz-Rodríguez, JM; Casado, JG; Pericuesta, E; Gutiérrez-Adán, A; González, E; Azkargorta, M; Conde, R; Bizkarguenaga, M; Embade, N; Elortza, ...
RESEARCH IN VETERINARY SCIENCE
2024

Hypomagnesaemia with varying degrees of extrarenal symptoms as a consequence of heterozygous CNNM2 variants
Bosman, W; Franken, GAC; de las Heras, J; Madariaga, L; Barakat, TS; Oostenbrink, R; van Slegtenhorst, M; Perdomo-Ramirez, A; Claverie-Martin, F; van Eerde, AM; Vargas-Poussou, R; Dubourg, LD; ...
SCIENTIFIC REPORTS
2024

Effect of Gracilaria vermiculophylla Macroalga on Non-Alcoholic Fatty Liver Disease in Obese Rats
González-Arceo, M; Aguirre, L; Macarulla, MT; Gil-Pitarch, C; Martínez-Chantar, ML; Portillo, MP; Gómez-Zorita, S;
ANTIOXIDANTS
2024

Membrane fission via transmembrane contact
Spencer, RKW; Santos-Pérez, I; Rodríguez-Renovales, I; Galvez, JMM; Shnyrova, AV; Müller, M;
NATURE COMMUNICATIONS
2024

Pten regulates endocytic trafficking of cell adhesion and Wnt signaling molecules to pattern the retina
Touahri, Y; Hanna, J; Tachibana, N; Okawa, S; Liu, H; David, LA; Olender, T; Vasan, L; Pak, A; Mehta, DN; Chinchalongporn, V; Balakrishnan, A; Cantrup, R; Dixit, R; Mattar, P; Saleh, F; Ilnytskyy, ...
CELL REPORTS
2024

Biochemical and structural impact of two novel missense mutations in cystathionine β- synthase gene associated with homocystinuria
Al-Sadeq, DW; Conter, C; Thanassoulas, A; Al-Dewik, N; Safieh-Garabedian, B; Martínez-Cruz, LA; Nasrallah, GK; Astegno, A; Nomikos, M;
BIOCHEMICAL JOURNAL
2024

Global and single-nucleotide resolution detection of 7-methylguanosine in RNA.
DAmbrosi, Silvia; Garcia-Vilchez, Raquel; Kedra, Darek; Vitali, Patrice; Macias-Camara, Nuria; Barcena, Laura; Gonzalez-Lopez, Monika; Aransay, Ana M; Dietmann, Sabine; Hurtado, Antonio; Blanco, ...
RNA biology
2024

Reinforcing the Evidence of Mitochondrial Dysfunction in Long COVID Patients Using a Multiplatform Mass Spectrometry-Based Metabolomics Approach
Martínez, S; Albóniga, OE; López-Huertas, MR; Gradillas, A; Barbas, C;
JOURNAL OF PROTEOME RESEARCH
2024

Probing altered receptor specificities of antigenically drifting human H3N2 viruses by chemoenzymatic synthesis, NMR, and modeling
Unione, L; Ammerlaan, ANA; Bosman, GP; Uslu, E; Liang, RA; Broszeit, F; van der Woude, R; Liu, YY; Ma, SZ; Liu, L; Gomez-Redondo, M; Bermejo, IA; Valverde, P; Diercks, T; Arda, A; de Vries, ...
NATURE COMMUNICATIONS
2024

Diverse crystalline protein scaffolds through metal-dependent polymorphism
Liutkus, M; Sasselli, IR; Rojas, AL; Cortajarena, AL;
PROTEIN SCIENCE
2024

Metallothionein-3 is a multifunctional driver that modulates the development of sorafenib-resistant phenotype in hepatocellular carcinoma cells
Rodrigo, MAM; Michalkova, H; Jimenez, AMJ; Petrlak, F; Do, T; Sivak, L; Haddad, Y; Kubickova, P; de los Rios, V; Casal, JI; Serrano-Macia, M; Delgado, TC; Boix, L; Bruix, J; Chantar, MLM; Adam, ...
BIOMARKER RESEARCH
2024

Retromer-mediated recruitment of the WASH complex involves discrete interactions between VPS35, VPS29, and FAM21
Romano-Moreno, M; Astorga-Simón, EN; Rojas, AL; Hierro, A;
PROTEIN SCIENCE
2024

Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination
Ayuso-García, P; Sánchez-Rueda, A; Velasco-Avilés, S; Tamayo-Caro, M; Ferrer-Pinós, A; Huarte-Sebastian, C; Alvarez, V; Riobello, C; Jiménez-Vega, S; Buendia, I; Cañas-Martin, J; Fernández-Susavila, ...
SCIENCE ADVANCES
2024

Rome III Criteria Capture Higher Irritable Bowel Syndrome SNP-Heritability and Highlight a Novel Genetic Link with Cardiovascular Traits
Tavares, LC; Lopera-Maya, EA; Bonfiglio, F; Zheng, TH; Sinha, T; Marques, FZ; Zhernakova, A; Sanna, S; DAmato, M;
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
2024

Catalytic specificity and crystal structure of cystathionine γ-lyase from Pseudomonas aeruginosa
Pedretti, M; Fernandez-Rodriguez, C; Conter, C; Oyenarte, I; Favretto, F; di Matteo, A; Dominici, P; Petrosino, M; Martinez-Chantar, ML; Majtan, T; Astegno, A; Martinez-Cruz, LA;
SCIENTIFIC REPORTS
2024

Vibrational spectroscopy coupled with machine learning sheds light on the cellular effects induced by rationally designed TLR4 agonists
Ami, D; Franco, AR; Artusa, V; Romerio, A; Shaik, MM; Italia, A; Anguita, J; Pasco, S; Mereghetti, P; Peri, F; Natalello, A;
TALANTA
2024

rhBMP-2 induces terminal differentiation of human bone marrow mesenchymal stromal cells only by synergizing with other signals
Kathami, N; Moreno-Vicente, C; Martin, P; Vergara-Arce, JA; Ruiz-Hernández, R; Gerovska, D; Aransay, AM; Araúzo-Bravo, MJ; Camarero-Espinosa, S; Abarrategi, A;
STEM CELL RESEARCH & THERAPY
2024

Targeting hepatic stellate cells to combat liver fibrosis: where do we stand?
Breitkopf-Heinlein, K; Martinez-Chantar, ML;
GUT
2024

Exploring kidney allograft rejection: A proof-of-concept study using spatial transcriptomics
Martin-Martin, C; Suarez-Alvarez, B; González, M; Torres, IB; Bestard, O; Martín, JE; Barceló-Coblijn, G; Moreso, F; Aransay, AM; Lopez-Larrea, C; Rodriguez, RM;
AMERICAN JOURNAL OF TRANSPLANTATION
2024

DNA methylation differences between the female and male X chromosomes in human brain.
Morgan, Robert; Loh, Eddie; Singh, Devika; Mendizabal, Isabel; Yi, Soojin V;
bioRxiv : the preprint server for biology
2024

Congenital erythropoietic porphyria
To-Figueras, J; Erwin, AL; Aguilera, P; Millet, O; Desnick, RJ;
LIVER INTERNATIONAL
2024

Proceedings of the 5th Meeting of Translational Hepatology, organized by the Spanish Association for the Study of the Liver (AEEH).
Alvarado-Tapias, Edilmar; Maya-Miles, Douglas; Albillos, Agustin; Aller, Rocio; Ampuero, Javier; Andrade, Raul J; Arechederra, Maria; Aspichueta, Patricia; Banales, Jesus M; Blas-Garcia, Ana; ...
Gastroenterologia y hepatologia
2024

Crystal-to-crystal polymerisation of monosubstituted [PW11O39Cu(H2O)]5- Keggin-type anions
Ruiz-Bilbao, E; Pache, A; Barrenechea, U; Reinoso, S; San Felices, L; Vivanco, MD; Lezama, L; Artetxe, B; Gutierrez-Zorrilla, JM;
DALTON TRANSACTIONS
2024

Darobactin Substrate Engineering and Computation Show Radical Stability Governs Ether versus C-C Bond Formation
Woodard, AM; Peccati, F; Navo, CD; Jiménez-Osés, G; Mitchell, DA;
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2024

Integration of proteomic and metabolomic analysis reveal distinct metabolic alterations of prostate cancer-associated fibroblasts compared to normal fibroblasts from patient's stroma samples
Bordanaba-Florit, G; Royo, F; Albóniga, OE; Clayton, A; Falcón-Pérez, JM; Webber, J;
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
2024

Electrostatics introduce a trade-off between mesophilic stability and adaptation in halophilic proteins
Herrero-Alfonso, P; Pejenaute, A; Millet, O; Ortega-Quintanilla, G;
PROTEIN SCIENCE
2024

Classical BSE dismissed as the cause of CWD in Norwegian red deer despite strain similarities between both prion agents
Marín-Moreno, A; Benestad, SL; Barrio, T; Pirisinu, L; Espinosa, JC; Tran, L; Huor, A; Di Bari, MA; Eraña, H; Maddison, B; DAgostino, C; Fernández-Borges, N; Canoyra, S; Jerez-Garrido, N; Castilla, ...
VETERINARY RESEARCH
2024

Mitochondrial antiviral signaling protein enhances MASLD progression via the ERK/TNFα/NFκβ pathway
Novoa, E; Lima, ND; Gonzalez-Rellan, MJ; Chantada-Vazquez, MDP; Verheij, J; Rodriguez, A; Esquinas-Roman, EM; Fondevila, MF; Koning, M; Fernandez, U; Cabaleiro, A; Parracho, T; Iglesias-Moure, ...
HEPATOLOGY
2024

Propionate and butyrate counteract renal damage and progression to chronic kidney disease
Corte-Iglesias, V; Saiz, ML; Andrade-Lopez, AC; Salazar, N; Bernet, CR; Martin-Martin, C; Borra, JM; Lozano, JJ; Aransay, AM; Diaz-Corte, C; Lopez-Larrea, C; Suarez-Alvarez, B;
NEPHROLOGY DIALYSIS TRANSPLANTATION
2024

A Multidisciplinary Structural Approach to the Identification of the Haemophilus influenzae Type b Capsular Polysaccharide Protective Epitope
Nonne, F; Dello Iacono, L; Bertuzzi, S; Unione, L; Proietti, D; Norais, N; Margarit, I; Adamo, R; Jiménez-Barbero, J; Carboni, F; Romano, MR;
ACS CENTRAL SCIENCE
2024

Disentangling Glycan-Protein Interactions: Nuclear Magnetic Resonance (NMR) to the Rescue
Bertuzzi, S; Poveda, A; Ardá, A; Gimeno, A; Jiménez-Barbero, J;
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
2024

Identification and validation of a blood- based diagnostic lipidomic signature of pediatric inflammatory bowel disease
Salihovic, S; Nyström, N; Mathisen, CBW; Kruse, R; Olbjorn, C; Andersen, S; Noble, AJ; Dorn-Rasmussen, M; Bazov, I; Perminow, G; Opheim, R; Detlie, TE; Huppertz-Hauss, G; Hedin, CRH; Carlson, ...
NATURE COMMUNICATIONS
2024

DNA methylation and stroke prognosis: an epigenome-wide association study
Jiménez-Balado, J; Fernández-Pérez, I; Gallego-Fábrega, C; Lazcano, U; Soriano-Tárraga, C; Vallverdú-Prats, M; Mola-Caminal, M; Rey-Alvarez, L; Macias-Gómez, A; Suárez-Pérez, A; Giralt-Steinhauer, ...
CLINICAL EPIGENETICS
2024

BirthSeq, a new method to isolate and analyze dated cells in different vertebrates
Rueda-Alaña, E; Grillo, M; Vázquez, E; Salas, SM; Senovilla-Ganzo, R; Escobar, L; Quintas, A; Benguria, A; Aransay, AM; Bengoa-Vergniory, N; Dopazo, A; Encinas, JM; Nilsson, M; García-Moreno, F;
DEVELOPMENT
2024

The strongest protein binder is surprisingly labile
Fernandez-Calvo, A; Reifs, A; Saa, L; Cortajarena, AL; De Sancho, D; Perez-Jimenez, R;
PROTEIN SCIENCE
2024

Antigenic determinants driving serogroup-specific antibody response to Neisseria meningitidis C, W, and Y capsular polysaccharides: Insights for rational vaccine design
Pietri, GP; Bertuzzi, S; Karnicar, K; Unione, L; Lisnic, B; Malic, S; Miklic, K; Novak, M; Calloni, I; Santini, L; Usenik, A; Romano, MR; Adamo, R; Jonjic, S; Turk, D; Jimenez-Barbero, J; Rovis, TL;
CARBOHYDRATE POLYMERS
2024

PCNA molecular recognition of different PIP motifs: Role of Tyr211 phosphorylation
Ruiz-Albor, A; Chaves-Arquero, B; Martín-Barros, I; Guerra-Castellano, A; Gonzalez-Magaña, A; de Opakua, AI; Merino, N; Ferreras-Gutiérrez, M; Berra, E; Díaz-Moreno, I; Blanco, FJ;
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
2024

IFNAR(-/-) Mice Constitute a Suitable Animal Model for Epizootic Hemorrhagic Disease Virus Study and Vaccine Evaluation
Jiménez-Cabello, L; Utrilla-Trigo, S; Benavides-Silván, J; Anguita, J; Calvo-Pinilla, E; Ortego, J;
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
2024

The lipopolysaccharide-TLR4 axis regulates hepatic glutaminase 1 expression promoting liver ammonia build-up as steatotic liver disease progresses to steatohepatitis
Mercado-Gómez, M; Goikoetxea-Usandizaga, N; Kerbert, AJC; Gracianteparaluceta, LU; Serrano-Macía, M; Lachiondo-Ortega, S; Rodriguez-Agudo, R; Gil-Pitarch, C; Simón, J; González-Recio, I; Fondevila, ...
METABOLISM-CLINICAL AND EXPERIMENTAL
2024

Human Brain Aging is Associated with Dysregulation of Cell-Type Epigenetic Identity.
Jeong, Hyeonsoo; Mendizabal, Isabel; Yi, Soojin V;
bioRxiv : the preprint server for biology
2024

Preovulatory follicular fluid secretome added to in vitro maturation medium influences the metabolism of equine cumulus-oocyte complexes
Luis-Calero, M; Ortiz-Rodríguez, JM; Fernández-Hernández, P; Muñoz-García, CC; Pericuesta, E; Gutiérrez-Adán, A; Marinaro, F; Embade, N; Conde, R; Bizkarguenaga, M; Millet, O; González-Fernández, ...
BMC VETERINARY RESEARCH
2024

Three-Dimensional Hepatocyte Spheroids: Model for Assessing Chemotherapy in Hepatocellular Carcinoma
Royo, F; Garcia-Vallicrosa, C; Azparren-Angulo, M; Bordanaba-Florit, G; Lopez-Sarrio, S; Falcon-Perez, JM;
BIOMEDICINES
2024

Lipidomics and biodistribution of extracellular vesicles-secreted by hepatocytes from Zucker lean and fatty rats.
Azparren-Angulo, Maria; Mleczko, Justyna; Alboniga, Oihane E; Kruglik, Sergei; Guigner, Jean-Michel; Gonzalez, Esperanza; Garcia-Vallicrosa, Clara; Llop, Jordi; Simo, Cristina; Alonso, Cristina; ...
Journal of extracellular biology
2024

Phosphorylation at the disordered N-end makes HuR accumulate and dimerize in the cytoplasm
Baños-Jaime, B; Corrales-Guerrero, L; Pérez-Mejias, G; Rejano-Gordillo, CM; Velázquez-Campoy, A; Martínez-Cruz, LA; Martínez-Chantar, ML; de la Rosa, MA; Díaz-Moreno, I;
NUCLEIC ACIDS RESEARCH
2024

Human CAZyme genes polymorphism and risk of IBS: a population-based study
Torices, L; Esteban-Blanco, C; Bozzarelli, I; Zamfir-Taranu, A; Bonfiglio, F; DAmato, M;
GUT
2024

Metabolic adaptations in prostate cancer
Pujana-Vaquerizo, M; Bozal-Basterra, L; Carracedo, A;
BRITISH JOURNAL OF CANCER
2024

Transition transferases prime bacterial capsule polymerization
Litschko, C; Di Domenico, V; Schulze, J; Li, SZ; Ovchinnikova, OG; Voskuilen, T; Bethe, A; Cifuente, JO; Marina, A; Budde, I; Mast, TA; Sulewska, M; Berger, M; Buettner, FFR; Lowary, TL; Whitfield, ...
NATURE CHEMICAL BIOLOGY
2024

Seroprevalence of adeno-associated virus types 1, 2, 3, 4, 5, 6, 8, and 9 in a Basque cohort of healthy donors
Navarro-Oliveros, M; Vidaurrazaga, A; Guerra, GS; Castellana, D; Embade, N; Millet, O; Marigorta, UM; Abrescia, NGA;
SCIENTIFIC REPORTS
2024

Quantifying Siglec-sialylated ligand interactions: a versatile 19F-T2 CPMG filtered competitive NMR displacement assay
Atxabal, U; Fernández, A; Moure, MJ; Sobczak, K; Nycholat, C; Almeida-Marrero, V; Oyenarte, I; Paulson, JC; de la Escosura, A; Torres, T; Reichardt, NC; Jiménez-Barbero, J; Ereño-Orbea, J;
CHEMICAL SCIENCE
2024

Solid-Phase-Supported Chemoenzymatic Synthesis and Analysis of Chondroitin Sulfate Proteoglycan Glycopeptides
Lin, PH; Xu, YM; Bali, SK; Kim, J; Gimeno, A; Roberts, ET; James, D; Almeida, NMS; Loganathan, N; Fan, F; Wilson, AK; Amster, IJ; Moremen, KW; Liu, J; Jimenez-Barbero, J; Huang, XF;
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
2024

Identification of Urine Metabolic Markers of Stroke Risk Using Untargeted Nuclear Magnetic Resonance Analysis
Oliveira, N; Sousa, A; Amaral, AP; Conde, R; Verde, I;
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2024

Cryogenic electron microscopy reveals morphologically distinct subtypes of extracellular vesicles among porcine ejaculate fractions
Parra, A; Barranco, I; Martínez-Díaz, P; González, E; Albóniga, OE; Cabrera, D; Falcón-Pérez, JM; Roca, J;
SCIENTIFIC REPORTS
2024

Pseudophosphorylation of single residues of the J-domain of DNAJA2 regulates the holding/folding balance of the Hsc70 system
Velasco-Carneros, L; Bernardo-Seisdedos, G; Maréchal, JD; Millet, O; Moro, F; Muga, A;
PROTEIN SCIENCE
2024

Nanotechnology-assisted intracellular delivery of antibody as a precision therapy approach for KRAS-driven tumors
López-Estévez, AM; Sanjurjo, L; Turrero, A; Arriaga, I; Abrescia, NGA; Poveda, A; Jimenez-Barbero, J; Vidal, A; Torres, D; Alonso, MJ;
JOURNAL OF CONTROLLED RELEASE
2024

Roughness affects the response of human fibroblasts and macrophages to sandblasted abutments
Romero-Gavilán, F; Arias-Mainer, C; Cerqueira, A; Peñarrocha-Oltra, D; Bernabeu-Mira, JC; García-Arnáez, I; Elortza, F; Muriach, M; Gurruchaga, M; Goñi, I; Suay, J;
BIOMEDICAL ENGINEERING ONLINE
2024

Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway
Gil-Pitarch, C; Serrano-Maciá, M; Simon, J; Mosca, L; Conter, C; Rejano-Gordillo, CM; Zapata-Pavas, LE; Peña-Sanfélix, P; Azkargorta, M; Rodríguez-Agudo, R; Lachiondo-Ortega, S; Mercado-Gómez, ...
CELL REPORTS MEDICINE
2024

The PP2A regulator IER5L supports prostate cancer progression
Crespo, JR; Martín-Martín, N; Garcia-Longarte, S; Corres-Mendizabal, J; Carlevaris, O; Astobiza, I; Zabala-Letona, A; Guiu, M; Azkargorta, M; Gonzalez-Lopez, M; Macías-Cámara, N; Doan, P; Elortza, ...
CELL DEATH & DISEASE
2024

Surface-Enhanced Raman Scattering Monitoring of Tryptophan Dynamics in 3D Pancreatic Tumor Models
Valera, PS; Henriques-Pereira, M; Wagner, M; Gaspar, VM; Mano, JF; Liz-Marzán, LM;
ACS SENSORS
2024

Dysfunctional VLDL metabolism in MASLD.
Marigorta, Urko M; Millet, Oscar; Lu, Shelly C; Mato, Jose M;
NPJ metabolic health and disease
2024

Metastatic hormone-naïve prostate cancer: a distinct biological entity
Corres-Mendizabal, J; Zacchi, F; Martín-Martín, N; Mateo, J; Carracedo, A;
TRENDS IN CANCER
2024

MetSCORE: a molecular metric to evaluate the risk of metabolic syndrome based on serum NMR metabolomics
Gil-Redondo, R; Conde, R; Bruzzone, C; Seco, ML; Bizkarguenaga, M; González-Valle, B; de Diego, A; Lain, A; Habisch, H; Haudum, C; Verheyen, N; Obermayer-Pietsch, B; Margarita, S; Pelusi, S; ...
CARDIOVASCULAR DIABETOLOGY
2024

Effect of Health Status and Heat-Induced Inactivation on the Proteomic Profile of Plasma Rich in Growth Factors Obtained from Donors with Chronic Inflammatory Skin Conditions
Anitua, E; Tierno, R; Azkargorta, M; Elortza, F; Alkhraisat, MH;
BIOMOLECULES
2024

Glucocorticoid receptor controls atopic dermatitis inflammation via functional interactions with P63 and autocrine signaling in epidermal keratinocytes
Sevilla, LM; Pons-Alonso, O; Gallego, A; Azkargorta, M; Elortza, F; Pérez, P;
CELL DEATH & DISEASE
2024

Genetic algorithms applied to translational strategy in metabolic-dysfunction associated steatohepatitis (MASH). Learning from mouse models
Martínez-Arranz, I; Alonso, C; Mayo, R; Mincholé, I; Mato, JM; Lee, DJ;
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
2024

Increased levels of circulating cell-free double-stranded nucleic acids in the plasma of glioblastoma patients.
Rackles, Elisabeth; Zaccheroni, Elena; Lopez, Patricia Hernandez; Faletti, Stefania; Bene, Massimiliano Del; DiMeco, Francesco; Pelicci, Giuliana; Falcon-Perez, Juan M;
Journal of extracellular biology
2024

Gold(III)-Induced Amide Bond Cleavage In Vivo: A Dual Release Strategy via π-Acid Mediated Allyl Substitution
Unnikrishnan, VB; Sabatino, V; Amorim, F; Estrada, MF; Navo, CD; Jimenez-Oses, G; Fior, R; Bernardes, GJL;
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2024

Insights into the recognition of hypermucoviscous Klebsiella pneumoniae clinical isolates by innate immune lectins of the Siglec and galectin families
Campanero-Rhodes, MA; Martí, S; Hernández-Ortiz, N; Cubero, M; Ereño-Orbea, J; Ardá, A; Jiménez-Barbero, J; Ardanuy, C; Solís, D;
FRONTIERS IN IMMUNOLOGY
2024

Combining sandblasting and pink anodisation of Ti implants as a promising method for improving fibroblast adhesion and immune response
Arias-Mainer, C; Romero-Gavilán, F; Cerqueira, A; Peñarocha-Oltra, D; Bernabeu-Mira, JC; Elortza, F; Azkargorta, M; Gurruchaga, M; Goñi, I; Suay, J;
JOURNAL OF MATERIALS CHEMISTRY B
2024

Insights into the transglucosylation activity of α-glucosidase from Schwanniomyces occidentalis
Merdzo, Z; Narmontaite, E; Gonzalez-Alfonso, JL; Poveda, A; Jimenez-Barbero, J; Plou, FJ; Fernández-Lobato, M;
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
2024

A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease
Conduit, SE; Pearce, W; Bhamra, A; Bilanges, B; Bozal-Basterra, L; Foukas, LC; Cobbaut, M; Castillo, SD; Danesh, MA; Adil, M; Carracedo, A; Graupera, M; McDonald, NQ; Parker, PJ; Cutillas, PR; ...
NATURE COMMUNICATIONS
2024

Influence of Selective Deoxyfluorination on the Molecular Structure of Type-2 N-Acetyllactosamine
Kurfirt, M; Stastna, LC; Dracinsky, M; Pohl, R; Cisarová, I; Sykora, J; Balouch, M; Baka, M; Hamala, V; Cañada, FJ; Ardá, A; Jiménez-Barbero, J; Karban, J;
JOURNAL OF ORGANIC CHEMISTRY
2024

An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD)
Vacca, M; Kamzolas, I; Harder, LM; Oakley, F; Trautwein, C; Hatting, M; Ross, T; Bernardo, B; Oldenburger, A; Hjuler, ST; Ksiazek, I; Lindén, D; Schuppan, D; Rodriguez-Cuenca, S; Tonini, MM; ...
NATURE METABOLISM
2024

AlphaFold2 Predicts Alternative Conformation Populations in Green Fluorescent Protein Variants
Núñez-Franco, R; Muriel-Olaya, MM; Jiménez-Osés, G; Peccati, F;
JOURNAL OF CHEMICAL INFORMATION AND MODELING
2024

Protocol for volume correlative light X-ray and electron microscopy of endothelial cells in mouse tissue.
Reglero-Real, Natalia; Perez-Gutierrez, Lorena; Saleeb, Rebeca S; Nourshargh, Sussan; Collinson, Lucy; Yoshimura, Azumi;
STAR protocols
2024

Polyoxometalate inhibition of SOX2-mediated tamoxifen resistance in breast cancer
Aurrekoetxea-Rodriguez, I; Lee, SY; Rábano, M; Gris-Cárdenas, I; Gamboa-Aldecoa, V; Gorroño, I; Ramella-Gal, I; Parry, C; Kypta, RM; Artetxe, B; Gutierrez-Zorrilla, JM; Vivanco, MD;
CELL COMMUNICATION AND SIGNALING
2024

Multiplex Determination of Glycan Profiles on Urinary Prostate-Specific Antigen by Quartz-Crystal Microbalance Combined with Surface-Enhanced Raman Scattering
Armero, L; Plou, J; Valera, PS; Serna, S; García, I; Liz-Marzán, LM;
ACS SENSORS
2024

Unprecedented selectivity for homologous lectin targets: differential targeting of the viral receptors L-SIGN and DC-SIGN
Delaunay, C; Pollastri, S; Thépaut, M; Cavazzoli, G; Belvisi, L; Bouchikri, C; Labiod, N; Lasala, F; Gimeno, A; Franconetti, A; Jiménez-Barbero, J; Ardá, A; Delgado, R; Bernardi, A; Fieschi, F;
CHEMICAL SCIENCE
2024

Enriching productive mutational paths accelerates enzyme evolution
Patsch, D; Schwander, T; Voss, M; Schaub, D; Hüppi, S; Eichenberger, M; Stockinger, P; Schelbert, L; Giger, S; Peccati, F; Jiménez-Osés, G; Mutny, M; Krause, A; Bornscheuer, UT; Hilvert, D; ...
NATURE CHEMICAL BIOLOGY
2024

The cell rejuvenation atlas: leveraging network biology to identify master regulators of rejuvenation strategies.
Arcos Hodar, Javier; Jung, Sascha; Soudy, Mohamed; Barvaux, Sybille; Del Sol, Antonio;
Aging
2024

Identification of PRMT5 as a therapeutic target in cholangiocarcinoma
Elurbide, J; Colyn, L; Latasa, MU; Uriarte, I; Mariani, S; Lopez-Pascual, A; Valbuena, E; Castello-Uribe, B; Arnes-Benito, R; Adan-Villaescusa, E; Martinez-Perez, LA; Azkargorta, M; Elortza, ...
GUT
2024

A Starch- and Sucrose-Reduced Diet Has Similar Efficiency as Low FODMAP in IBS-A Randomized Non-Inferiority Study
Roth, B; Nseir, M; Jeppsson, H; DAmato, M; Sundquist, K; Ohlsson, B;
NUTRIENTS
2024

Iron chelation as a new therapeutic approach to prevent senescence and liver fibrosis progression
Amengual, J; Alay, A; Vaquero, J; Gonzalez-Sanchez, E; Bertran, E; Sánchez, A; Herrera, B; Meyer, K; Maus, M; Serrano, M; Martínez-Chantar, ML; Fabregat, I;
CELL DEATH & DISEASE
2024

Development of bioactive solid-foam scaffolds from decellularized cartilage with chondrogenic and osteogenic properties
Mendibil, U; Lópiz-Morales, Y; Arnaiz, B; Ruiz-Hernández, R; Martín, P; Di-Silvio, D; Garcia-Urquia, N; Elortza, F; Azkargorta, M; Olalde, B; Abarrategi, A;
MATERIALS TODAY BIO
2024

Constipation is associated with an increased risk of major adverse cardiac events in a UK population.
Zheng, Tenghao; Camargo Tavares, Leticia; DAmato, Mauro; Marques, Francine Z;
American journal of physiology. Heart and circulatory physiology
2024

Worldwide Prevalence and Description of Cyclic Vomiting Syndrome According to the Results of the Rome Foundation Global Epidemiology Study.
Izagirre, Arantzazu; Sarasqueta, Cristina; Flores-Arriaga, Joel; Aso, Maria C; Perez Perez, Maria; Tack, Jan; Huang, I-Hsuan; Sperber, Ami D; Palsson, Olafur S; Bangdiwala, Shrikant I; DAmato, ...
The American journal of gastroenterology
2024

Beyond basic characterization and omics: Immunomodulatory roles of platelet-derived extracellular vesicles unveiled by functional testing
Palviainen, M; Puutio, J; Ostergaard, RH; Eble, JA; Maaninka, K; Butt, U; Ndika, J; Kari, OK; Kamali-Moghaddam, M; Kjaer-Sorensen, K; Oxvig, C; Aransay, AM; Falcon-Perez, JM; Federico, A; Greco, ...
JOURNAL OF EXTRACELLULAR VESICLES
2024