Seminar

Automated NMR protein structure calculation

Prof. Peter Güntert

New methods for the NMR spectra analysis, assignment and structure calculation make it possible to assign the chemical shifts and calculate the three-dimensional structure of proteins automatically without the need for time-consuming and error-prone manual work. The talk will give an overview of modern NMR methods for protein structure analysis and present recent developments, including the structure determination of a protein inside living cells, membrane proteins, symmetric multimer proteins, and solid state NMR structure determination of amyloid fibrils.