Activity Detail
Seminar
Role of JunD in the control of oxidative stress, aging and cancer development
Dr. Fatima Mechta-Grigoriou
Reactive oxygen species (ROS) are implicated in the pathophysiology of various diseases, including cancer. In this study, we show that JunD, a member of the AP- 1 family of transcription factors, reduces tumor angiogenesis by limiting Rasmediated production of ROS.