CIC bioGUNE research projects cover a variety of areas, from chemistry and biochemistry to biomedicine, including cell growth and differentiation, cancer, the innate immune response, liver disease, chromatin remodeling, intracellular trafficking processes, as well as the knowledge of the structure of proteins, ribosomes, and viruses.

• Molecular Recognition and Host-Pathogen Interactions

  We study cellular processes and pathogenic mechanisms against cancer cells, viruses, bacteria and prions. We aim at understanding the immune response against cancer cells and developing innovative technologies to fight them. We also elucidate the interaction processes of infectious microorganisms with mammalian cells to modulate response and achieve better treatments by employing a synergic combination of biochemical, cellular, and structural methodologies.

• Metabolism and Cell Signaling in Disease

  We investigate metabolism and signaling implicated in prostate, liver, and breast cancer. We elucidate pathways implicated in neurodegeneration, liver diseases, and several rare diseases. We also focus on identifying relevant molecular and cellular targets for a more precise medicine and to provide Society with predictive and prognostic non-invasive biomarkers.